A Comparative Study of Transfer Learning-Based DeepLearning Models for Breast Cancer Detection

A Comparative Study of Transfer Learning-Based DeepLearning Models for Breast Cancer Detection

Author: Md. Sahiqur Rahman, Sabikunnahar Swarna, Prosenjit Mojumder, Shahadat Hossain Research & Reviews: A Journal of Medical Science and Technology-STM Journals Issn: 2319-3417 Date: 2026-02-21 11:07 Volume: 15 Issue: 01 Keyword: Breast cancer detection, computer-aided diagnosis (CAD), deep learning, denseNet121, medical image analysis, ResNet50, transfer learning Full Text PDF Submit Manuscript Journals

Abstract

Breast cancer is a major concern in the world today, and early and accurate diagnosis is most crucial
in the case of breast cancer, as it is among the disorders where the total cost of loss of life is high.
Traditional screening processes are subjective and vulnerable to inter-observer reliability issues and
diagnostic errors, being primarily based on manual interpretation of medical images. To address these limitations, Deep Learning (DL) is now a leading approach for medical image analysis. However, training deep Convolutional Neural Networks (CNNs) from scratch remains a significant drawback due to the small sizes of labeled medical datasets. This paper gives an in-depth comparison of five state-of- the-art Transfer Learning (TL) models, which comprise VGG16, VGG19, ResNet50, DenseNet121, and MobileNet models, and apply them to undertake automated classification of breast cancer. Optimization of models was performed on the publicly available dataset, and more demanding data augmentation procedures were employed to lower overfitting levels and enhance generalization characteristics. Several measures of accuracy, precision, recall, F1-score, and computational complexity were used to measure performance. According to experimental results, DenseNet121 achieved a higher overall testing accuracy of 98.85% and an F1-score of 98.40, owing to effective feature propagation. MobileNet, on its part, showed outstanding computational powers and an accuracy of 94.50%, which means that it is feasible in resource-constrained mobile health activities. This paper proves that transfer learning is the most effective method to maximize the diagnosis accuracy and reduce the computation costs incurred to generate a highly formidable Computer-Aided Diagnosis (CAD) structure to directly
help radiologists make important clinical decisions.

Keyword: Breast cancer detection, computer-aided diagnosis (CAD), deep learning, denseNet121, medical image analysis, ResNet50, transfer learning

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